The healthcare system's laboratory is both its most and its least utilised resource. In recent years, with the development of very complicated laboratory procedures and sophisticated gear connected to computers and lab information systems, laboratory testing has undergone significant evolution. The demand for better patient care has increased along with the growth of laboratory services. More direct patient contact is required for laboratory professionals in front-line roles in healthcare teams made up of doctors, nurses, pharmacists, and other healthcare professionals in order to provide evidence-based and patient-centered treatment.


Histopathological Profile of Therapeutic Doses of Methanolic Extract Combination of Tea and Mango Mistletoes in Cardiac of Preventive Hypertensive Rats (DOCA-salt) Model
Durrotul Hasanah, Nour Athiroh Abdoes Sjakoer, Nurul Jadid Mubarakati

Tea and mango mistletoes have to lower blood pressure by improving oxidative stress and endothelial dysfunction. The flavonoid compounds found in these two mistletoes act as antihypertensives. Hypertension is a risk factors that influences the incidence of cardiac disease. This study examines the histopathological of the cardiac of hypertensive rats (preventive model) after treatment of methano

Potential of Garlic Filtrate as An Alternative Anticoagulant for Whole Blood Samples
Ari Nuswantoro, Jessica Ningtyas Berlianti

Synthetic anticoagulants such as heparin, citric, and ethylenediaminetetraacetic acid (EDTA) are commonly used to prevent blood clots. In contrast, its widespread use in clinical laboratories is still constrained by price, its toxic nature, and its short shelf life. Therefore, an alternative material that is relatively cheap, non-toxic, and easy to obtain and process in a ready-to-use form is n

Differences in Diameter of the Growth Inhibition Zone of Klebsiella pneumonia Bacteria After Incubation at 37°C and 25°C
Juwy Trianes, Bastian Bastian, Dewi Hartati

Pneumonia is an infection that causes the largest death in children worldwide (South Sumatra Province), which occupies the 6th position. One of the laboratory re-identification of Klebsiella pneumonia is a multi-antibiotic testing. The high sensitivity antibiotic that is still used is amikacin. The uniqueness of the diameter of the inhibition zone using the antibiotic amikac

Validation of Rapid Antibody (IgM – IgG) Test Kit for SARS-CoV-2 Infection in Surabaya, Indonesia
Museyaroh Museyaroh, Puspa Wardani, Aryati Aryati, Evy Diah Woelansari

At the beginning of the Corona Virus Disease 2019 (COVID-19) pandemic, rapid test examinations were widely used as a screening for Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection. The purpose of this examination was to detect SARS-CoV-2 IgM/IgG antibodies in the patient's body. One of these tests uses the immunochromatographic method. This study aims to determine the vali

Neutrophil Lymphocyte Ratio (NLR) in COVID-19 Patients Receiving Convalescent Plasma Therapy
Desyani Ariza, Andi Maya Kesrianti, Tazya Anggraini Ruslan

Recently, a new RNA virus from the Coronaviridae family was discovered, known as SARS-Cov-2. This virus causes pneumonia and inflammation in the body. One of the laboratory tests used to see inflammation in the body is the Neutrophil Lymphocyte Ratio, or often abbreviated as NLR. NLR is one of the markers of inflammation that can be used simply, efficiently, and reliably because of its high sta

Effect of Bay Leaf (Syzygium polyanthum) Extract on Antioxidant Activity, MDA Levels, and Liver Histopathology Feature of Ethambutol Induced Wistar Rats
Bambang Edi Suwito, Lea Maera Shanty, Retna Gumilang, Handayani Handayani, Renata Alya Ulhaq

Bay leaf extract (Syzygiun polianthum) is one herbal elemnt that may be used to lessen liver function issues, lessen symptops of nausea, vomiting, discomfort and improve adherence and the effectiveness of tuberculossi treatment. The objective of this study was to determine the effect of bay leaf (Syzygium polyanthum) extract on antioxidant activity, Malondialdehyde (MDA) level

The Effect of Cigarette Smoking Duration on Hemoglobin Level Measured with Cyanmethemoglobin Method
Fitriani Kahar, Ririh Jatmi Wikandari, Irnawati Irnawati, Martha Silpa Penmaley

In Indonesia, cigarette consumption is quite prevalent and has been become more common over time. According to Riskesdas (Baseline Health Research from Agency of Health Research and Development) study in 2018, the national percentage of people aged who smoke increased from 2016-2018, namely from 3.39% in 2016, 3.9% in 2017 and 9.65% in 2018. Smoking habits will negatively affect human health. C

Relationship of Albumin Concentrations with Sodium, Potassium, in CAPD (Continuous Ambulatory Peritoneal Dialysis) Patients at PHC Hospital Surabaya
Dian Anggraini, Edy Haryanto, Syamsul Arifin, Ayu Puspitasari

Kidney failure is caused by a permanent decline in kidney function and requires renal replacement therapy, one of which is Continuous Ambulatory Peritoneal Dialysis (CAPD). This study aimed to determine the relationship between albumin concentrations and sodium and potassium concentrations in CAPD patients. The study was carried out between January to May 2022. Cross-sectional research methodol