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Adyan Donastin Aisyah Aisyah

Abstract

Diabetic foot ulcers (DFU) are complications in people with diabetes mellitus (DM) in the form of wounds or tissue damage resulting in vascular insufficiency and or neuropathy that can develop into an infection. Early detection of germs of diabetic foot ulcers may be used as a recommendation of empirical therapy before the definitive treatment based on culture results and appropriate antibiotics treatment, which may reduce hospitalization time and amputation events. According to Riskesdas in 2013, state that the number of antibiotic used without prescriptions in Indonesia about 86.1%. The study aims to retrospectively analyze the bacterial culture and drug susceptibility test results for patients with diabetic foot ulcers (DFU) in Jemursari Islamic Hospital Surabaya during 2012–2016 to help clinicians choose a more appropriate empirical antibiotic treatment for DFU. This study used cross–sectional designed with retrospective approaches, which analyzed descriptively and samples were taken by the total sampling of 11 samples. This research was conducted at Islamic Hospital of Jemursari Surabaya in May–September 2017 by using medical record data which are outpatient and inpatients who treatment at Jemursari Islamic Hospital. The result was found 6 types of bacteria consisting of Staphylococcus aureus (18%), Staphylococcus non–haemolytic (18%), Klebsiella pneumonia (27%), Enterobacter aerogenes (18%), Burkholderia cepacia (9%), Escheria coli (9%). The most sensitive antibiotics in the Gram–positive bacteria in this study are Amikacin, Teicoplanin and Oxacillin and the most resistant to Amoxicillin and Ampicillin whereas the most sensitive antibiotics in the Gram–negative bacteria in this study were Meropenem and the most resistant to Ciprofloxacin and Trimethroprim–sulfamethoxazole.

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How to Cite
Donastin, A. and Aisyah, A. (2019) “MICROBIAL PATTERN OF DIABETIC FOOT ULCER PATIENT IN JEMURSARI ISLAMIC HOSPITAL SURABAYA PERIOD 2012-2016”, Indonesian Journal of Medical Laboratory Science and Technology, 1(1), pp. 22–32. doi: 10.33086/ijmlst.v1i1.914.
Section
Articles
Microbial pattern, antibiotics sensitivity pattern, diabetic, foot ulcer, diabetes mellitus

References

Shahbazian, H. Yazdanpanah,L. Latifi, S. 2013. Risk Assessment of patients with diabetes for foot ulcers according to risk classification consensus of International Working Group on Diabetic Foot (IWGDF). Pak J Med Sci, 29. PP.730-734.

Whiting, D. Guariguata, L, Weil,C, Shaw, J. 2011. IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Res Clin Pract, 94. Pp. 311-321.

Shaw,J. Sicree, R. Zimmet, P. 2010. Global estimates of the prevalence of diabeters for 2010 and 2030. Diabetes Res Clin Pract, (87), pp.4-14.

Suyono, S. 2014. Diabetes Melitus di Indonesia. In Alwi, A.S.B.M.S.S.S.Buku Ajar Ilmu Penyakit Dalam, 6th ed. Jakarta:Interna Publishing.

Aragon-sanchex, J. Lazaro-Martinez, J. Pulido-Duque, J. Maynar, M. 2012. From the diabetic foot ulcer and beyond: How do foot infections spread in patients with diabetes? Diabetic Foot and Ankle, 3(10), p. 18693.

Boulton, A. Armstrong, D. Albert, S. 2008. Comprehensive foot exam and risk assessment: a report of the American Diabetes Association task force on foot care. Diabetes Care, 31, PP. 79-85.

Gardner, S. Hillis, S. Heilmann, K. Segre, J. 2013. The Neuropathic Diabetic Foot Ulcer Microbiome is Associated With Clinical Factors. Diabates Journal. 62.

WHO, 2016. Global Report on Diabetes. France: WHO Press.

Van Acker, K. Campillo, N. 2015. Diabetic Foot Disease: When the alarm to action is missing. Diabetes Voice, (2), pp.14-16. Available at: www.idf.org/diabetesvoice.online-issue-2-july-2015/van-acker [Accessed 5 Januari 2017].

Waspadhi, S. 2014. Kaki Diabetes. In Setiati, Alwi, Sudoyo and Simadibrata. Kaki Diabetes Buku Ajar Ilmu Peyakit Dalam. 6th ed. Jakarta:Interna Publishing. Pp.2369-2376.

Yusuf, S. Okuwa, M. Irwan, M, Rassa,S. 2016. Prevalence and Risk Factor of Diabetic Foot Ulcers in a Regional Hospital, Eastern Indonesia, Open Journal of Nursing, 6, pp.1-10.

Zubair, M. Malik, A. Ahmad, J. 2015, Diabetic Foot Ulcer: A Review, American Journal of Internal Medicine, 3(2), pp.28-49.

Decroli, E. Karimi, J.Manaf, A. Syahbuddin, S. 2008. Profil Ulkus Diabetik pada Penderita Rawat Inap di bagian Penyakit dalam RSUP Dr. M Djamil Padang. P.58.

Adhitama, L. 2013. Evaluasi Pemilihan antibiotika berdasarkan uji kultur kuman dan sensitivitas antibiotika pada ganggren diabetik di bangsal rawat inap RSUD Gambiran Kota Kediri, Jurnal Universitas Gajah Mada, p.44.

Tarigan, L. 2011. Karakteristik penderita diabetes melitus dengan komplikasi yang dirawat inap di RSU Herna Medan Tahun 2009-2010. Medan: Universitas Sumatera Utara.

Chudlori, B. 2013. Pola Kuman dan Resistensinya terhadap Antibiotika dari Spesimen Pus di RSUD Dr. Moewardi Tahun 2012. Universitas Gajah Mada.

Suharjo,J. Chayono, B. 2007. Manajemen Ulkus Kaki Diabetik. Dexa Media.

Frykberb, R. 2002. Risk Factor, Pathogenesis and Management of Diabetic Foot Ulcers. Iowa: Des Moines University.

Gaol, Y. Erly, Sy, E. 2017. Pola Resistensi bakteri aerob pada ulkus diabetik terhadap beberapa antibiotik di laboratorium mikrobiologi RSUP Dr. M. Djamil Padang Tahun 2011-2013. Jurnal Kesehatan Andalas, 6(1).

Commons, R.J. 2015. High Burden of Diabetic Foot Infections in The top End of Australia: An Emerging Health Crisis (DEFINE study). Diabetes Res Clin Pract.

Danmusa, U. Nasir, I. Ahmad, A. Muhammad, H. 2016. Prevalence and healthcare costs associated with the management of diabetic foot ulcer in patients attending Ahmadu Bello University Teaching Hospital, Nigeria. International Journal of Health Sciences, 10(2). Pp. 219-228.

Chomi, E. Nuneza, O. 2014. Clinical Profile and Prognosis of Diabetes Mellitus Type 2 Patients with Diabetic Foot Ulcers in Chomi Medical and Surgical. Philipines: Departement of Biological Sciences, College of Science and Mathematics, Mindanao State University-Iligan Institute of Technology.

Deribe, B. Woldemichael K. Nemera,G. 2014. Prevalence and Factors influencing Diabetic Foot Ulcer Among Diabetic Patients Attending Arbaminch Hospital, South Ethiopia, J. Diabetes Metab, 2, p.322.

Fahmi, M. 2015. Profil pasien ulkus diabetik di Rumah Sakit Umum Daerah Cengkareng Tahun 2013-2014.

Witanto, D. Yudhi, H, Sandy.2009. Gambaran Umum Perawatan Ulkus Diabetikum pada Pasien Rawat Inap Rumah Sakit Immonuel Bandung Periode Juli 2007-Agustus 2008. Bandung:Fkaultas Kedokteran Kristen Maranatha.

Peters, B. Jabra-rizk, M. Costerton, J. Shirtliff, M. 2012. Polymicrobial Interactions: Impacr on Pathogenesis and Human Disease. Clinical Microbiology Reviews, 25(1).pp.193-213.

Smith, T. 1999. Emergence of vancomycin resitance in Staphylococcus aureus. New England Journal of Medicine, (340),pp.493-501.

Chaudry, W. Badar, R. Jamal, M. Jeong, J. 2015. Clinico-microbiological study and antibiotic resistance profile of mercA and ESBL gene prevalence in patients with diabetic foot infections. Experimental anda Therapeutic Medicine, 11. Pp.1031-38.

Akbar, G.T., Karimi, J. Anggraini, D. 2014. Pola Bakteri dan Resistensi Antibiotik pada Ulkus Kaki Diabetik Grade dua di RSUD Arifin Achmad Periode 2012. JOM, 1(2).

Adyan Donastin, Department of Medicine, Faculty of Medicine, Universitas Nahdlatul Ulama Surabaya, Surabaya, Indonesia

Aisyah Aisyah, Department of Medicine, Faculty of Medicine, Universitas Nahdlatul Ulama Surabaya, Surabaya, Indonesia