Analysis of Determinants of Anemia Incidence in Third Trimester Pregnant Women
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Megawati Sinambela
Alfi Syahri
Rotua Sumihar Sitorus
Abstract
Anemia in third-trimester pregnant women increases the risk of pregnancy complications such as preterm labor and low birth weight. Contributing factors include adherence to iron tablet consumption, maternal age, parity, nutritional status, and compliance with antenatal care (ANC) visits. This study aims to analyze the determinants of anemia in third-trimester pregnant women at the Gunung Selamat Labuhan Batu Health Center. This cross-sectional study involved 96 third-trimester pregnant women selected using consecutive sampling. Data were collected through interviews, hemoglobin level examinations, and evaluations of iron tablet adherence, nutritional status, and ANC visits. Data analysis used bivariate (chi-square) and multivariate (logistic regression) tests. Bivariate analysis showed a significant relationship between anemia and iron tablet adherence (p=0.00; PR=5.95), maternal age (p=0.00; PR=5.11), parity (p=0.00; PR=4.95), nutritional status (p=0.00; PR=7.55), and ANC visit compliance (p=0.00; PR=8.55). Multivariate analysis identified nutritional status (p=0.00; Exp(B)=16.69) and ANC visit compliance (p=0.00; Exp(B)=14.51) as the most dominant factors influencing anemia. Nutritional status and ANC visit compliance are key determinants of anemia in third-trimester pregnant women. Interventions focusing on nutritional education, ANC service optimization, and increased adherence to iron supplementation are essential to reduce anemia prevalence among pregnant women
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Copyright (c) 2025 Megawati Sinambela, Alfi Syahri, Rotua Sumihar Sitorus
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References
Ahmed, R. H., Yussuf, A. A., Ali, A. A., Iyow, S. N., Abdulahi, M., Mohamed, L. M., & Mohamud, M. H. T. (2021). Anemia among pregnant women in internally displaced camps in Mogadishu, Somalia: a cross-sectional study on prevalence, severity and associated risk factors. BMC Pregnancy and Childbirth, 21(1), 832. https://doi.org/10.1186/s12884-021-04269-4 DOI: https://doi.org/10.1186/s12884-021-04269-4
Al-Nuzaili, M. A. (2023). Prevalence of anemia and associated risk factors among pregnant women in Sana’a, Yemen. Sana’a University Research Journals, 2(1). https://doi.org/10.59628/jchm.v2i1.107 DOI: https://doi.org/10.59628/jchm.v2i1.107
Asres, A. W., Hunegnaw, W. A., Ferede, A. G., & Azene, T. W. (2022). Compliance level and factors associated with iron–folic acid supplementation among pregnant women in Dangila, Northern Ethiopia: A cross-sectional study. SAGE Open Medicine, 10. https://doi.org/10.1177/20503121221118989 DOI: https://doi.org/10.1177/20503121221118989
Cindy Narita Kusuma Astuti, Budi Prasetyo, & Dewi Setyowati. (2023). The effect of iron tablets’ side effects on the level of compliance to consuming iron tablets in pregnant woman: A systematic review. World Journal of Advanced Research and Reviews, 17(1), 395–403. https://doi.org/10.30574/wjarr.2023.17.1.0037 DOI: https://doi.org/10.30574/wjarr.2023.17.1.0037
Diana, S., Wahyuni, C. U., & Prasetyo, B. (2020). Maternal Complications and Risk Factors for Mortality. Journal of Public Health Research, 9(2). https://doi.org/10.4081/jphr.2020.1842 DOI: https://doi.org/10.4081/jphr.2020.1842
Esem, O. (2023). Nutritional Status and Compliance with Blood Supplemental Tablets as a Cause of Anemia in Pregnant Women. EMBRIO, 15(2), 150–158. https://doi.org/10.36456/embrio.v15i2.7396 DOI: https://doi.org/10.36456/embrio.v15i2.7396
Fernández-Batanero, J. M., Montenegro-Rueda, M., & Fernández-Cerero, J. (2022). Use of Augmented Reality for Students with Educational Needs: A Systematic Review (2016–2021). Societies, 12(2), 36. https://doi.org/10.3390/soc12020036 DOI: https://doi.org/10.3390/soc12020036
Fitriana Ikhtiarinawati Fajrin, Khusnul Nikmah, Lilik Darwati, & Nining Istighosah. (2023). Pregnancy Anemia its Relation to Low Birth Weight (Lbw) Incidence. International Journal of Educational and Life Sciences, 1(4). https://doi.org/10.59890/ijels.v1i4.944 DOI: https://doi.org/10.59890/ijels.v1i4.944
Jasa, N. E., & Listiana, A. (2023). Parity, Age Related To The Incidence Of Anemia In Pregnant Women. Jurnal Kebidanan Malahayati, 9(3), 415–420. https://doi.org/10.33024/jkm.v9i3.10646 DOI: https://doi.org/10.33024/jkm.v9i3.10646
Karagiannidis, C., Mostert, C., Hentschker, C., Voshaar, T., Malzahn, J., Schillinger, G., Klauber, J., Janssens, U., Marx, G., Weber-Carstens, S., Kluge, S., Pfeifer, M., Grabenhenrich, L., Welte, T., & Busse, R. (2020). Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study. The Lancet Respiratory Medicine, 8(9), 853–862. https://doi.org/10.1016/S2213-2600(20)30316-7 DOI: https://doi.org/10.1016/S2213-2600(20)30316-7
Khanam, A., Vohra, K., Achary MG, T., Ranjith, A., Bharti, H., Ghosh, R., Kaur, R., & Yadav, K. (2022). A Systematic review of factors affecting compliance toward oral iron-folic acid supplementation among pregnant women in India. Indian Journal of Community Health, 34(4), 456–463. https://doi.org/10.47203/IJCH.2022.v34i04.002 DOI: https://doi.org/10.47203/IJCH.2022.v34i04.002
M Afolabi, B., Adelusi, V. A., Folayan, W., Akinmoladun, O. B., Egunjobi, F., Ozor, L., Afolabi, T. M., Fagbemi, T., & M Afolabi, B. (2020). Evaluating the impact of preventive interventions against malaria during antenatal care of pregnant women from 2014 to 2018 in Ondo State, Southwest Nigeria. Obstetrics & Gynecology International Journal, 11(1). https://doi.org/10.15406/ogij.2020.11.00485 DOI: https://doi.org/10.15406/ogij.2020.11.00485
Ngonzi, J., Tibaijuka, L., Kintu, T. M., Kihumuro, R. B., Onesmus, A., Onesmus, B., Adong, J., Salongo, W., Boatin, A. A., & Bebell, L. M. (2023). Prevalence and risk factors for newborn anemia in southwestern Uganda: a prospective cohort study. https://doi.org/10.21203/rs.3.rs-3054549/v1 DOI: https://doi.org/10.21203/rs.3.rs-3054549/v1
Ngonzi, J., Tibaijuka, L., Mwanje Kintu, T., Kihumuro, R. B., Ahabwe, O., Byamukama, O., Salongo, W., Adong, J., Boatin, A. A., & Bebell, L. M. (2024). Prevalence and Risk Factors for Newborn Anemia in Southwestern Uganda: A Cross-Sectional Study. Anemia, 2024, 1–7. https://doi.org/10.1155/2024/5320330 DOI: https://doi.org/10.1155/2024/5320330
Noviyanti, B., Simanjuntak, H. C., Hutasoit, E. S. P., Silitonga, H. A., & Julianto, E. (2019). The Relationship between Social Economic Levels and Anemia Events in Pregnant Women in Glugur Darat Health Center. Journal of Maternal and Child Health, 4(6), 48–56. https://doi.org/10.26911/thejmch.2019.04.06.05 DOI: https://doi.org/10.26911/thejmch.2019.04.06.05
Orwa, J., Mantel, M., Mugerwa, M., Brownie, S., Pallangyo, E. S., Mwasha, L., Isangula, K., Subi, L., Mrema, S., Edwards, G., Siso, D., Selestine, E., Mwansisya, T., Mbekenga, C., & Temmerman, M. (2019). Maternal healthcare services use in Mwanza Region, Tanzania: a cross-sectional baseline survey. BMC Pregnancy and Childbirth, 19(1), 474. https://doi.org/10.1186/s12884-019-2653-4 DOI: https://doi.org/10.1186/s12884-019-2653-4
Ouzennou, N., Amor, H., & Baali, A. (2019). Socio-economic, cultural and demographic profile of a group of Moroccan anaemic pregnant women. African Health Sciences, 19(3), 2654–2659. https://doi.org/10.4314/ahs.v19i3.41 DOI: https://doi.org/10.4314/ahs.v19i3.41
Pitale, D. L. (2018). The effects of food habits on pregnancy outcome. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 7(2), 622. https://doi.org/10.18203/2320-1770.ijrcog20180183 DOI: https://doi.org/10.18203/2320-1770.ijrcog20180183
Riskesdas. (2018). National report of Basic Health Research (Riskesdas) 2018. Health Research and Development Agency, Ministry of Health, Indonesia. Ministry of Health, Republic of Indonesia.
Saaka, M., Oladele, J., Larbi, A., & Hoeschle-Zeledon, I. (2017). Dietary Diversity Is Not Associated with Haematological Status of Pregnant Women Resident in Rural Areas of Northern Ghana. Journal of Nutrition and Metabolism, 2017, 1–10. https://doi.org/10.1155/2017/8497892 DOI: https://doi.org/10.1155/2017/8497892
Seu, M. M. V., Mose, J. C., Panigoro, R., & Sahiratmadja, E. (2019). Anemia Prevalence after Iron Supplementation among Pregnant Women in Midwifes Practice of Primary Health Care Facilities in Eastern Indonesia. Anemia, 2019, 1–8. https://doi.org/10.1155/2019/1413906 DOI: https://doi.org/10.1155/2019/1413906
Srour, M. A., Aqel, S. S., Srour, K. M., Younis, K. R., & Samarah, F. (2018). Prevalence of Anemia and Iron Deficiency among Palestinian Pregnant Women and Its Association with Pregnancy Outcome. Anemia, 2018, 1–7. https://doi.org/10.1155/2018/9135625 DOI: https://doi.org/10.1155/2018/9135625
Suryanarayana, R., Santhuram, A., Chandrappa, M., Shivajirao, P., & Rangappa, S. (2016). Prevalence of anemia among pregnant women in rural population of Kolar district. International Journal of Medical Science and Public Health, 5(3), 454. https://doi.org/10.5455/ijmsph.2016.2307201575 DOI: https://doi.org/10.5455/ijmsph.2016.2307201575
Ugwa, E. (2016). Nutritional practices and taboos among pregnant women attending antenatal care at general hospital in Kano, Northwest Nigeria. Annals of Medical and Health Sciences Research, 6(2), 109. https://doi.org/10.4103/2141-9248.181846 DOI: https://doi.org/10.4103/2141-9248.181846
Umuro, D. S., Asres, Y. L., & Muluneh, G. M. (2019). Magnitude and factors associated with anemia among pregnant women attending antenatal care at st. Paul’s Hospital Millennium Medical college, Addis Ababa, Ethiopia, July, 2019. https://doi.org/10.21203/rs.2.13046/v1 DOI: https://doi.org/10.21203/rs.2.13046/v1
Varghese, J. S., Swaminathan, S., Kurpad, A. V., & Thomas, T. (2019). Demand and supply factors of iron-folic acid supplementation and its association with anaemia in North Indian pregnant women. PLOS ONE, 14(1), e0210634. https://doi.org/10.1371/journal.pone.0210634 DOI: https://doi.org/10.1371/journal.pone.0210634
WHO. (2021). Anaemia in women and children: A global public health problem. World Health Organization. WHO (World Health Organization).
Yadav, U. K., Ghimire, P., Amatya, A., & Lamichhane, A. (2020). Predictors of Anemia Among Pregnant Women of Under-privileged Ethnic Groups Attending Antenatal Care at Provincial Level Hospital of Province 2, Nepal. https://doi.org/10.21203/rs.3.rs-57411/v1 DOI: https://doi.org/10.21203/rs.3.rs-57411/v1
Yuliarti, Y., Ermi, N., & Arinda, D. F. (2022). The Causes of Malnutrition for Pregnant Mothers Analysis and The Impact on the COVID-19 Pandemic. Jurnal Ilmu Kesehatan Masyarakat, 13(2), 210–223. https://doi.org/10.26553/jikm.2022.13.2.210-223 DOI: https://doi.org/10.26553/jikm.2022.13.2.210-223
