Consanguinity via Breastfeeding in view of Islam and Science of Epigenetics
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Abstract
Background : One of the unique features of the Qur´an and Sunna is that never contradict the Science. Quran is not considered as a scientific book, however, includes many extraordinary signs and true scientific facts that have not been known at the time of the Quran revelation. Over the past few decades, several of them have been revealed, but many are still waiting to be uncovered.
Result : Breastfeeding is the most natural and safest way to provide nutrition, protection and unique bonding experience for newborn babies. The term “milk-kinship” is a kind of relationship via breastfeeding that was established hundreds of years ago via the Qur´an and Sunna. The study revealed that the life expectancy of the F2 offspring obtained from milk-sublings mating was much shorter than the offspring from control group. Which mean that there is period in which offspring are susceptible to breast milk induced epigenetic changes, especially in the first 2 years of life.
Conclusion : Recent research suggests that consanguinity via breastfeeding can be explained by heritable mechanism of epigenetic modifications.
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References
Alsaweed, M., Lai, CT., Hartmann, PE., Geddes, DT., Kakulas F., 2016. Human Milk Cells Contain Numerous miRNAs that May Change with Milk Removal and Regulate Multiple Physiological Processes. Int J Mol Sci. 17(6):956. doi: 10.3390/ijms17060956. PMID: 27322254; PMCID: PMC4926489. DOI: https://doi.org/10.3390/ijms17060956
Bodo, C,, and Melnik, GS., 2017. DNA methyltransferase 1-targeting miRNA-148a of dairy milk: a potential bioactive modifier of the human epigenome. Funct. Foods Health Dis. 7: 671–687. doi: 10.31989/ffhd.v7i9.379. DOI: https://doi.org/10.31989/ffhd.v7i9.379
Chutipongtanate, S., Morrow, AL., Newburg, DS., 2022. Human Milk Extracellular Vesicles: A Biological System with Clinical Implications. Cells 11: 2345. https://doi.org/10.3390/ cells11152345. DOI: https://doi.org/10.3390/cells11152345
Daud, N., Ali, Z., Ismail, H., Jamani, NA., and Mohd, SR., 2020. The Implementation of Shariah Compliant Human Milk Bank for Premature Infants in Malaysia. Journal of Critical Reviews 7(16): 1007-1012.
Dror, DK., Allenm LH., 2018. Overview of nutrients in humanmilk. Adv. Nutr. 9:278S–294S. doi: 10.1093/advances/nmy022. DOI: https://doi.org/10.1093/advances/nmy022
Ghaly, M., 2018. Human Milk-Based Industry in the Muslim World: Religioethical Challenges. Breastfeeding Medicine 13(S1), S-28-S-29. DOI: https://doi.org/10.1089/bfm.2018.29081.mjg
Ghareeb, Bilal AA., 2010. Genetics of diseases, ethics and beauty in selection of mates (an Islamic perspective). Medical Journal of Islamic World Academy of Sciences 18(4): 155-164.
Ghareeb, Bilal AA., 2011. Human Genetics and Islam: Scientific and Medical aspects. JIMA Vol 43: pp.83. DOI: https://doi.org/10.5915/43-2-7014
Golan, Y., Assaraf, YG., 2020. Genetic and Physiological Factors Affecting Human Milk Production and Composition. Nutrients 12(5):1500. doi: 10.3390/nu12051500. PMID: 32455695; PMCID: PMC7284811. DOI: https://doi.org/10.3390/nu12051500
Hilliard, TS., Gaisina, IN., Muehlbauer, AG., Gaisin, AM., Gallierm F., and Burdette, JE. 2011. Glycogen synthase kinase 3beta inhibitors induce apoptosis in ovarian cancer cells and inhibit in-vivo tumor growth. Anticancer Drugs 22: 978–985. DOI: https://doi.org/10.1097/CAD.0b013e32834ac8fc
Horta, BL., Loret de Mola, C., Victor,a CG., 2015. Long-term consequences of breastfeeding on cholesterol, obesity, systolic blood pressure and type 2 diabetes: a systematic review and meta-analysis. Acta Paediatr. 104(467):30-7. doi: 10.1111/apa.13133. PMID: 26192560. DOI: https://doi.org/10.1111/apa.13133
Ibn Hajar al-Asqalani: Fath al Bari fi Sharh Sahih al-Bukhari. Hadith 4814, In: Abu Amina Elias. Adult breastfeeding in Islam 2013 https://www.abuaminaelias.com/islam-adult-breastfeeding/
Ibn Kathir AI., 1999. In S.M. Al-Salamah (Ed.), Tafsir al-Qur’an al-‘Azim Dar Taybah (2).Vol. 1: pp. 633–635).
Jackson, M., Marks, L., May, GHW., Wilson, JB., 2018. The genetic basis of disease. Essays Biochem. 62(5):643-723. doi: 10.1042/EBC20170053. Erratum in: Essays Biochem. 2020 Oct 8;64(4):681. PMID: 30509934; PMCID: PMC6279436. DOI: https://doi.org/10.1042/EBC20170053
Kakulas, F., 2015. Breast milk: A source of stem cells and protective cells for the infant. Infant 11:187–191.
Linner, A., and Almgren, M., 2020. Epigenetic programming-the important first 1000 days. Acta Paediatr. 109: 443–452. doi: 10.1111/apa.15050. DOI: https://doi.org/10.1111/apa.15050
Meng, F., Henson, R., Wehbe-Janek, H., Ghoshal, K., Jacob, ST., Patel, T. 2007. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133: 647–658. DOI: https://doi.org/10.1053/j.gastro.2007.05.022
Moro, EM., Billeaud, C., Rachel B., 2019: Processing of donor human milk: update and recommendations from the European Milk Bank Association (EMBA). DOI: https://doi.org/10.3389/fped.2019.00049
Musnad Ahmed 931. https://sunnah.com/ahmad:931
Naumova, OY., Odintsova, VV., Arincina, IA., Rychkov, SY., Muhamedrahimov, RJ., Shneider, YV., et al., 2019. A Study of the Association between Breastfeeding and DNA Methylation in Peripheral Blood Cells of Infants. Russ. J. Genet. 55:749–755. DOI: https://doi.org/10.1134/S1022795419060103
Ozkan, H., Tuzun, F., Kumral, A., Duman, N., 2012. Milk kinship hypothesis in light of epigenetic knowledge. Clin Epigenetics. 4(1):14. DOI: https://doi.org/10.1186/1868-7083-4-14
Ozkan, H., Tuzun,, F., Taheri, S., Korhan, P., Akokay, P., et al., 2020. Epigenetic Programming Through Breast Milk and Its Impact on Milk-Siblings Mating. Front Genet. 2(11):569232. DOI: https://doi.org/10.3389/fgene.2020.569232
Peterson, B. 2016. The Presence of Stem Cells in Human Breast Milk and Research Implications. Senior Thesis Liberty University,
Qur´an. Sahih International. English Translation. https://corpus.quran.com/.
Reif, S., Elbaum Shiff, Y., Golan-Gerstl, R., 2019. Milk-derived exosomes (MDEs) have a different biological effect on normal fetal colon epithelial cells compared to colon tumor cells in a miRNA-dependent manner. J. Transl. Med. 17:325. doi: 10.1186/s12967-019-2072-3. DOI: https://doi.org/10.1186/s12967-019-2072-3
Sahih Muslim, 1500a. https://sunnah.com/muslim:1500a
Sahih Muslim, 1453b. https://quranx.com/hadith/Muslim/Reference/Hadith-1453/
Smyczynska, U., Bartlomiejczyk, MA., Stanczak, MM., Sztromwasser, P., Wesolowska, A., Barbarska, O. et al., 2020. Impact of processing method on donated human breast milk microRNA content. PLoS ONE 15: e0236126. DOI: https://doi.org/10.1371/journal.pone.0236126
Subudhi, S., Sriraman, N., 2021. Islamic Beliefs About Milk Kinship and Donor Human Milk in the United States. Pediatrics. 147(2):e20200441. DOI: https://doi.org/10.1542/peds.2020-0441
Sunan Ibn Majah (1942). https://sunnah.com/ibnmajah:1942
Sunan Ibn Majah (1938). https://sunnah.com/ibnmajah:1938
Templeman, NM., and Murphy, CT., 2018. Regulation of reproduction and longevity by nutrient-sensing pathways. J. Cell Biol. 217: 93–106. doi: 10.1083/jcb.201707168 DOI: https://doi.org/10.1083/jcb.201707168
Tingö, L., Ahlberg, E., Johansson, L., Pedersen, SA., Chawla, K., Sætrom, P., et al., 2021. Non-Coding RNAs in Human Breast Milk: A Systematic Review. Front Immunol. 12:725323. doi: 10.3389/fimmu.2021.725323. PMID: 34539664; PMCID: PMC8440964. DOI: https://doi.org/10.3389/fimmu.2021.725323
Wan Yusuff Wan Mazwati and Mashitah Zainol Abidin, 2022. A scoping review of wet nursing in the muslim world. JURNAL ISLAM DAN MASYARAKAT KONTEMPORARI. 23(2): 58-82
World Health Organisation. Infant and young child feeding, 2021. https://www.who.int/news-room/fact-sheets/detail/infant-and-young-child-feeding