The Use of Prophylactic Antibiotics on Orthopaedic Procedures in an Academic Hospital in Indonesia
Article Sidebar
Main Article Content
Abstract
Background: Surgical site infections (SSIs) are common surgical complications that will increase cost of treatment. The incidence of SSI can be prevented with antibiotic prophylactic. Uncompliance using of prophylactic antibiotics is one of the factors leading to the occurrence a microbes resistance. The data on the using of prophylactic antibiotics in Indonesia is still limited. Objective: This study aims to analyze the using of prophylactic antibiotic guideline on orthopaedic surgery. Methods: The study was conducted retrospectively using data from medical records on patients who had clean and clean-contaminated orthopedic procedures from 2013 to 2016 in the standard operating room of Dr. Soetomo hospital Surabaya. We analyzed the use of prophylactic antibiotics in terms of antibiotic selection, timing of administration, and the compliance to the prophylactic antibiotic local guidelines on orthopaedic surgery. Results: Overall, patient data from 2013 to 2016 was 5246 patients. The compliance rate of prophylactic antibiotics from 2013 to 2016 was 48.3%. This level of compliance uses a selection of antibiotics, dose of administration, delivery mode, delivery time, and route of administration. Conclusion: The results of this study have shown that the prophylactic antibiotic compliance rate on orthophaedic procedures in Soetomo Hospital from 2013 to 2016 was 48,3%. Antibiotic resistance control program quite effective at increasing compliance with the use of the prophylaxis antibiotics.
Downloads
Article Details
Copyright (c) 2021 Yuani Setiawati, Azmi Farhadi
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
References
Agodi, A., Quattrocchi, A., Barchitta, M., Adornetto, V., Cocuzza, A., Latino, R., et al., 2015, Risk of surgical site infection in older patients in a cohort survey: Targets for quality improvement in antibiotic prophylaxis. Int Surg 100(3):473–9.
Al-Mulhim, FA., Baragbah, MA., Sadat-Ali, M., Alomran, AS., Azam, MQ., 2014, Prevalence of surgical site infection in orthopedic surgery: a 5-year analysis. Int Surg 99(3):264-268.
ASHP, 2013, Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery. Available St : https://www.ashp.org/guidelines/therapeutic-guidelines-antimicrobial-prophylaxis.pdf (accesed 7 Februari 2017).
Baktijasa, B., Wibisono, S., Wahyuni, S., Herwanto, B., Farida, S., Worokarti, Susariani H., 2009, “Pedoman Penggunaan antibiotik Rumah Sakit Umum Daerah Dokter Soetomo”, edisi IV
Bratzler, DW., Dellinger. EP., Olsen, KM., et al., 2013, Clinical practice guidelines for antimicrobial prophylaxis in surgery. Surg Infect (Larchmt) 14(1):73-156.
Bratzler, DW., Dellinger, EP., Olsen, KM et al., 2013, Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J Health-Syst Pharm. 70:195-283
Gagliardi, AR., Fenech, D., Eskicioglu, C. Nathens, AB., McLeod, R., 2009, Factors influencing antibiotic prophylaxis for surgical site infection prevention in general surgery: A review of the literature. Can J Surg 52(6):481-489. doi:10.1016/S0008-428X(09)50187-7
Hawn, MT., Richman, JS., MD, Vick, CC et al., 2013, Timing of Surgical Antibiotic Prophylaxis and the Risk of Surgical Site Infection. JAMA Surg. 148(7):649-657
JP, S., 2013, Penelitian Retrospektif : Angka Kejadian Surgical Site Infection (SSI) Pada Fiksasi Internal Fraktur Tertutup di Gedung Bedah Pusat Terpadu RSUD dr. Soetomo Surabaya Dalam Kurun Waktu Januari 2011-Desember 2012. Surabaya.
Lin, S., Mauffrey, C., Hammerberg, EM., Stahel, PF., Hak, DJ., 2014, Surgical site infection after open reduction and internal fixation of tibial plateau fractures. Eur J Orthop Surg Traumatol 24(5):797–803.
Manniën, J., van Kasteren, MEE., Nagelkerke, NJ., Gyssens, IC., Kullberg, BJ., Wille, JC et al., 2006, Effect of optimized antibiotic prophylaxis on the incidence of surgical site infection. Infect Control Hosp Epidemiol 27(12):1340–6
Mistry, V., Pandya, A., Chaudhari, J., Sondarva, D., Pillai, A., Hotchandani, S., 2013, Use of antimicrobial prophylaxis in clean elective orthopedic surgical procedures and identifying common infective organisms. Int J Med Sci Public Heal 2(4):994-1001.
Musmar, SM., Ba’ba, H., Owais H., 2014 Adherence to guidelines of antibiotic prophylactic use in surgery: a prospective cohort study in North West Bank, Palestine.
Ong, DT., Paraton, H K., 2014, The Pattern Of Antibiotic Prophylaxis In Clean and Clean Contaminated Surgical Procedure At Dr Soetomo Hospital.
Sánchez-Santana, T., del-Moral-Luque, JA., Gil-Yonte, P., Bañuelos-Andrío, L., Durán-Poveda, M., Rodríguez-Caravaca, G., 2017, Effect of compliance with an antibiotic prophylaxis protocol in surgical site infections in appendectomies. Prospective cohort study. Cirugía y Cir (English Ed. 85(3):208-213. doi:10.1016/j.circen.2017.05.013
Syachroni, S., 2015, Antibiotic prophylaxis compliance for clean-contaminated wounds in a district hospital in Jakarta. Heal Sci J Indones 6(1):57-62.
Thangarajah, T., Prasad, PS., Narayan, B., 2009, Surgical Site Infections Following Open Reduction and Internal Fixation of Ankle Fractures. Open Orthop J 3(1):56-60. doi:10.2174/1874325000903010056
Tiemann, AH., Hofmann, GO., 2009, Principles of the therapy of bone infections in adult extremities. Strateg Trauma Limb Reconstr 4(2):57-64.
(US) NC for HS, (US) NHDS, 2010, National Hospital Discharge Survey. US Department of Health and Human Services, Centers for Disease Control and Prevention