The Impact of Docosahexaenoic Acid (DHA) Supplementation on Calcium Levels in Third Trimester Pregnant Women with Chronic Energy Deficiency (CED): A Correlational Study
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Abstract
Background: Chronic Energy Deficiency (CED) during pregnancy represents a critical health challenge, especially in developing regions, where it significantly threatens maternal and fetal well-being. Docosahexaenoic Acid (DHA), an essential omega-3 fatty acid, plays a pivotal role in fetal neurodevelopment and maternal health. However, the impact of DHA supplementation on maternal calcium levels, particularly among pregnant women affected by CED, has not been extensively studied. This study evaluate the correlation between DHA supplementation and calcium levels in third-trimester pregnant women with CED, with the goal of improving outcomes for this vulnerable population.
Method and Results: This research uses experimental cohort study design with a quantitative approach, using non-probability sampling techniques such as quota and purposive sampling, and involving a total of 24 participants. Statistical analysis revealed a significant increase in calcium levels following DHA supplementation, with a p-value of 0.007 (<0.05), indicating a notable impact of the intervention. The mean calcium levels post-treatment were higher than pre-treatment, demonstrating the efficacy of DHA supplementation in improving calcium levels. Further analysis showed no significant correlation between pre-supplementation calcium levels and Body Mass Index (BMI) (p = 0.622, > 0.05). However, a significant correlation was found between post-supplementation calcium levels and BMI (p = 0.002, < 0.05). These findings indicate a positive correlation between DHA supplementation and calcium levels in pregnant women with CED during the third trimester. However, further investigation is needed to fully understand the relationship between calcium levels and BMI.
Conclusion: This study lays the groundwork for future research aimed at optimizing therapeutic interventions or supplementation strategies to improve the nutritional status of underweight pregnant women.
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Copyright (c) 2024 Rahajoe Imam Santosa, Salmon Charles Siahaan, Erik Jaya Gunawan, Florence Pribadi, Eirene Putri Febriani Pratama Bueya
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References
Fitria SY, Suhartini, Yani RWE. Analysis of Determinant Factors of Chronic Energy Deficiency (CED) in Pregnant Women With Modification of Lawrence Green and Snehandu B. Kar’s Theories. J Ilmu Kesehat Masy. 2024;14(3):381–92.
Angraini DI, Aryani LD, Sari MI, Imantika E. The Effect of Chronic Energy Deficiency and Protein Intake on the Incidence of Preeclampsia in Dr . H . Abdul Moeloek Hospital Lampung Province. Int Conf Innov Soc Sci Educ [Internet]. 2020;705–15. Available from: http://repository.lppm.unila.ac.id/25219/
Siahaan SC, Henderi H, Sudibjo, Safitiri NPD, Wakas BE, Pratama MFI. Intervensi Ibu Hamil Dengan Kurang Energi Kalori Melalui Suplementasi Mikronutrien Di SurabayaTahun 2019. Maj Kedokt Andalas [Internet]. 2021;44(1):17–27. Available from: http://jurnalmka.fk.unand.ac.id
Basak S, Mallick R, Banerjee A, Pathak S, Duttaroy AK. Maternal supply of both arachidonic and docosahexaenoic acids is required for optimal neurodevelopment. Nutrients. 2021;13(6):1–28.
Ryan BA, Kovacs CS. Maternal and fetal vitamin D and their roles in mineral homeostasis and fetal bone development. J Endocrinol Invest [Internet]. 2021;44(4):643–59. Available from: https://doi.org/10.1007/s40618-020-01387-2
Elbahnasawy AS, Valeeva ER, El-Sayed EM, Stepanova NV. Protective effect of dietary oils containing omega-3 fatty acids against glucocorticoid-induced osteoporosis. J Nutr Heal. 2019;52(4):323–31.
Kim N, Lee JO, Lee HJ, Kim HI, Kim JK, Lee YW, et al. Endogenous ligand for GPR120, docosahexaenoic acid, exerts benign metabolic effects on the skeletal muscles via AMP-activated protein kinase pathway. J Biol Chem [Internet]. 2015;290(33):20438–47. Available from: http://dx.doi.org/10.1074/jbc.M115.657379
Stavrinou PS, Andreou E, Aphamis G, Pantzaris M, Ioannou M, Patrikios IS, et al. The effects of a 6-month high dose omega-3 and omega-6 polyunsaturated fatty acids and antioxidant vitamins supplementation on cognitive function and functional capacity in older adults with mild cognitive impairment. Nutrients. 2020;12(2):1–17.
Ren XH, Yao YS, He LP, Jin YL, Chang WW, Li J, et al. Overweight and obesity associated with increased total serum calcium level: Comparison of cross-sectional data in the health screening for teaching faculty. Biol Trace Elem Res. 2013;156(1–3):74–8.
Mohieldein AH, Moshawah SAA, Elhabiby MI, Mustafa AA. Association of Total Serum Calcium Level with Obesity Markers (Body Mass Index and Waist Circumference) among Healthy Young Saudis. Pakistan J Med Heal Sci. 2023;17(4):348–51.