KORELASI KADAR KREATININ SERUM DENGAN HASIL TES ALBUMIN URINE PADA PASIEN DENGAN PENYAKIT GINJAL DI RSUD dr. SOEGIRI LAMONGAN

Abstract

Abstract: Examination of blood creatinine levels is one of the parameters used to assess renal
function, since serum and urinary excretion concentrations within 24 hours are relatively constant.
However, in another clinical guideline, there is a type of examination that is more recommended in
most patients with the risk of kidney failure, urine albumin test. In the event of renal dysfunction,
the ability of creatinine filtration will decrease and serum creatinine will increase as well as some
substances that should not exist in the urine, such as albumin, to appear. Reduced albumin excretion in the urine may be able to slow the rate of renal failure and help to delay the body’s need for
kidney or dialysis transplantation. This cross-sectional study aims to analyze the relationship between serum creatinine and albuminuria in patients with kidney disease. Serum creatinine level
examination by Jaffe method and urine albumin examination were qualitatively performed on the
respondents who met the inclusion criteria. A total of 92 data were then analyzed by Chi-square
with α<0,05. The results of this study indicate that there is a significant relationship between
serum creatinine and albuminuria levels in patients with general kidney disease (p = 0.000, r =
0.728), and in male patients (p = 0.000, r = 0.736) and females (p = 0,000; r = 0.686) with the
age level 41-50 years. There is no relationship between serum creatinine and albuminuria in male
and female patients at the age of 20-30 years and 31–40 years.