The Role Of Tea Tree Oil as A Skin Antimicrobial : A Literature Study
Keywords:tea tree oil, Melaleuca alternifolia, skin infection, microorganism
Background: Skin disease due to microorganism infection are still widely found in community. The infections can be caused by bacteria, viruses, fungi, and parasite. Tea tree oil often used as a herbal medicine in the treatment of skin diseases due to microorganisms. This literature study is conducted to review the role of tea tree oil as an antimicrobial in skin infections.
Method: Fifteen indexed journals published from 2015 to 2020 about tea tree oil and skin infections, were included. From 15 journals, 9 journals discuss antibacterial activity of tea tree oil, 2 journals discuss antiviral activity, 9 journals discuss antifungal activity, and 1 journal discusses antiparasitic activity. All journals state that tea tree oil has an antimicrobial effect on microorganisms that cause skin infections.
Result: From 9 journals, it was found that A. baumanni, P. aeruginosa, and C. acnes were the most sensitive bacteria to tea tree oil in terms of MIC and S. epidermidis was the most sensitive bacteria, seen from their inhibition zone. Eight journals state variations with significant differences in the activity of tea tree oil as an anti-fungal. Tea tree oil has stronger antibacterial activity than antifungal activity. It also has antiviral activity against HSV and antiparasitic on S. scabiei.
Conclusion: The conclusion of this study is that tea tree oil has antimicrobial activity against microorganisms that cause skin disease, including bacteria, viruses, fungi, and parasite.
Meza-Romero R, Navarrete-Dechent C, Downey C. Molluscum contagiosum: An update and review of new perspectives in etiology, diagnosis, and treatment. Clin Cosmet Investig Dermatol. 2019;12:373–81.
Yadav E, Kumar S, Mahant S, Khatkar S, Rao R. Tea tree oil: a promising essential oil. J Essent Oil Res [Internet]. 2017;29(3):201–13. Available from: http://dx.doi.org/10.1080/10412905.2016.1232665
Mertas A, Garbusińska A, Szliszka E, Jureczko A, Kowalska M, Król W. The influence of tea tree oil (Melaleuca alternifolia) on fluconazole activity against fluconazole-resistant candida albicans strains. Biomed Res Int. 2015;2015.
Thomas J, Carson CF, Peterson GM, Walton SF, Hammer KA, Naunton M, et al. Therapeutic potential of tea tree oil for scabies. Am J Trop Med Hyg. 2016;94(2):258–66.
Brun P, Bernabè G, Filippini R, Piovan A. In Vitro Antimicrobial Activities of Commercially Available Tea Tree (Melaleuca alternifolia) Essential Oils. Curr Microbiol. 2019;76(1):108–16.
Rajeshnidhi KR, Mahesh R. Antibacterial activity of tea tree oil against clinical isolates of Pseudomonas aeruginosa. Front Microbiol. 2019;10(JULY):1422–4.
Esmael A, Hassan MG, Amer MM, Abdelrahman S, Hamed AM, Abd-raboh HA, et al. Antimicrobial activity of certain natural-based plant oils against the antibiotic-resistant acne bacteria. Saudi J Biol Sci [Internet]. 2020;27(1):448–55. Available from: https://doi.org/10.1016/j.sjbs.2019.11.006
Sakkas H, Gousia P, Economou V, Sakkas V, Petsios S, Papadopoulou C. In vitro antimicrobial activity of five essential oils on multidrug resistant Gram-negative clinical isolates. J Intercult Ethnopharmacol. 2016;5(3):212–8.
Taleb MH, Abdeltawab NF, Shamma RN, Abdelgayed SS, Mohamed SS, Farag MA, et al. Origanum vulgare L. Essential oil as a potential anti-acne topical nanoemulsion—in vitro and in vivo study. Molecules. 2018;23(9).
Ziółkowska-Klinkosz M, Kedzia A, Meissner HO, Kedzia AW. Evaluation of the tea tree oil activity to anaerobic bacteria - In vitro study. Acta Pol Pharm - Drug Res. 2016;73(2):389–94.
Li WR, Li HL, Shi QS, Sun TL, Xie XB, Song B, et al. The dynamics and mechanism of the antimicrobial activity of tea tree oil against bacteria and fungi. Appl Microbiol Biotechnol. 2016;100(20):8865–75.
Ramadan MA, Shawkey AE, Rabeh MA, Abdellatif AO. Promising antimicrobial activities of oil and silver nanoparticles obtained from Melaleuca alternifolia leaves against selected skin-infecting pathogens. J Herb Med [Internet]. 2020;20(June):100289. Available from: https://doi.org/10.1016/j.hermed.2019.100289
Tullio V, Roana J, Scalas D, Mandras N. Enhanced killing of candida krusei by polymorphonuclear leucocytes in the presence of subinhibitory concentrations of melaleuca alternifolia and “mentha of Pancalieri” essential oils. Molecules. 2019;24(21).
Francisconi RS, Huacho PMM, Tonon CC, Bordini EAF, Correia MF, Sardi J de CO, et al. Antibiofilm efficacy of tea tree oil and of its main component terpinen-4-ol against Candida albicans. Braz Oral Res. 2020;34:e050.
Narang J, Narang R, Singh B, Kahlon S, George J, Dogra A. Comparative efficacy of tea tree oil nanoemulgel and clove oil nanoemulgel against Candida albicans. Int J Pharm Investig. 2018;8(1):50.
Patturaja K, Geetha R V. Evaluation of antimycotic activity of three essential oils on candida albicans -an invitro study. J Pharm Sci Res. 2017;9(4):480–2.
Fang F, Candy K, Melloul E, Bernigaud C, Chai L, Darmon C, et al. In vitro activity of ten essential oils against Sarcoptes scabiei. Parasites and Vectors [Internet]. 2016;9(1):1–7. Available from: http://dx.doi.org/10.1186/s13071-016-1889-3
How to Cite
Copyright (c) 2021 Dian Ardiana
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.