Factors Influencing Mortality In Neonates With Gastroschisis In Bali, Indonesia
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Made Sukmawati
Putu Mas Vina Paramitha Cempaka
I Made Kardana
Putu Junara Putra
I Wayan Dharma Artana
Made Indira Dianti Sanjiwani
Abstract
Gastroschisis is a congenital abdominal wall defect requiring immediate surgical
intervention. The high mortality rate in gastroschisis patients, particularly in developing
countries, underscores the importance of a deeper understanding of factors that may
influence clinical outcomes. This study aims to analyze factors affecting the risk of
mortality in neonates with gastroschisis. A retrospective cohort study was conducted
over five years and included 37 neonates with gastroschisis who were treated in the
neonatal intensive care unit at Prof. I.G.N.G. Ngoerah Hospital. The majority of subjects
were male (54.1%) and preterm (62.2%), with 18 patients (48.6%) surviving and 19
(51.4%) deceased. Surgical management primarily involved primary closure compared
to staged closure, with most closures occurring within the first day of life. Sixteen
subjects were identified with complex gastroschisis. The risk of mortality decreased by
56% in the simple gastroschisis group compared to the complex gastroschisis group (RR
0.44; 95% CI 0.23–0.87; p=0.01). The risk of mortality was found to be lower in
neonates with simple gastroschisis compared to those with complex gastroschisis. There
were no significant differences in mortality risk based on the method of closure, timing
of closure, or incidence of sepsis.
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Copyright (c) 2026 Made Sukmawati, Putu Mas Vina Paramitha Cempaka, I Made Kardana, Putu Junara Putra, I Wayan Dharma Artana, Made Indira Dianti Sanjiwani
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
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